Notify individuals of the potential risk of life-threatening respiratory depression, like information that the chance is best when starting OXYCONTIN or if the dosage is amplified, Which it could possibly arise even at suggested dosages.
The upper strengths of the drug (a lot more than 40 milligrams per tablet) really should be employed only For those who have been on a regular basis using reasonable to massive quantities of an opioid soreness medication. These strengths may bring about overdose (even Loss of life) if taken by a individual who hasn't been on a regular basis having opioids.
Take into consideration prescribing naloxone When the patient has residence associates (such as small children) or other near contacts at risk for accidental ingestion or overdose.
Neonates whose mothers have taken oxycodone chronically may exhibit respiratory melancholy and/or withdrawal signs or symptoms, possibly at beginning and/or from the nursery.
Precautions In advance of taking oxycodone, tell your physician or pharmacist When you are allergic to it; or to other opioid ache relievers (including oxymorphone); or if you have some other allergy symptoms.
living in a household wherever you will find small youngsters or a person who has abused street or prescription drugs getting prescription or around-the-counter medicines, natural vitamins, or herbal dietary supplements. Having OXYCONTIN with certain other medicines might cause serious Negative effects that may cause Demise.
The dosage is based on the professional medical ailment and response to procedure. Tend not to increase your dose, take the medication far more often, or take it for an extended time than prescribed. Properly quit the medication when so directed.
The danger for critical respiratory issues is higher when you start this medication read more and after a dose raise, or if you are taking the incorrect dose/toughness. Using this medication with Liquor or other drugs that could potentially cause drowsiness or respiratory difficulties may well bring about pretty severe Unintended effects, including Dying. Also, other medications can influence the removal more info of oxycodone from your body, which can have an effect on how oxycodone works.
MAOIs have been claimed to intensify the effects of not less than 1 opioid drug creating panic, confusion and considerable despair of respiration or coma. Using oxycodone hydrochloride tablets just isn't recommended for clients getting MAOIs or within fourteen times of halting these kinds of cure.
If concomitant use is critical, think about dosage reduction of OXYCONTIN till secure drug outcomes are realized. Consider individuals at frequent intervals for respiratory despair and sedation.
To reduce the chance of choking or possessing issues swallowing the tablet, choose just one a tablet at any given time if your dose is for more than one tablet. Don't pre-soak, lick, or wet the tablet right before positioning it in your mouth. Make sure to drink ample drinking water with Every single tablet to swallow it absolutely.
The following dosing details is for use only in pediatric sufferers eleven years and more mature already receiving and tolerating opioids for a get more info minimum of five consecutive days. For the two days instantly previous dosing with OXYCONTIN, sufferers have to be getting no less than 20 mg each day of oxycodone or its equivalent.
The danger for intense breathing difficulties is higher when you start this medication and after a dose enhance, or if you are taking the incorrect dose/energy. Using this medication with Liquor or other drugs that might cause drowsiness or respiration issues read more may perhaps result in extremely critical Negative effects, including Dying. Also, other medicines can have an affect on the removal of oxycodone/acetaminophen from a human body, which may influence how it really works.
Concomitant usage of OXYCONTIN with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could lessen oxycodone plasma concentrations, lessen opioid efficacy or, potentially, result in a withdrawal click here syndrome inside of a individual who experienced produced Actual physical dependence to oxycodone.